Mother and infant in a global pandemic of coronavirus infection. New challenges to the health care system
DOI:
https://doi.org/10.15574/PP.2020.82.17Keywords:
infection, coronavirus, COVID-19, CDC, pregnancy, childbirth, newborns, breastfeeding, immunizationAbstract
Coronavirus 2019 (COVID-19) is a potentially severe acute respiratory infection, caused by coronavirus-2. The virus is transmitted by airborne droplets, airborne dust, faecal-oral route. The source of coronavirus infection is a sick person. The vulnerable groups in the development of coronary virus disease are the pregnant women and their newborn babies.
This article analyse the latest global recommendations for the management and prevention of coronavirus disease (or/and suspecting) in pregnant women infected by COVID-19 and in their newborns, as well as in infants in outpatient service, and epidemiology of outbreaks prevention, and recommendations for breastfeeding and immunization.
References
AAP’s: Guidance on Providing Pediatric Ambulatory Services via Telehealth During COVID-19. (2020, April). URL: https://services.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections2/guidance-on-providing-pediatric-ambulatory-services-via-telehealth-during-covid-19/
American College of Obstetricians and Gynecologists/Society for Maternal-Fetal Medicine: Outpatient Assessment and Management for Pregnant Women With Suspected or Confirmed Novel Coronavirus (COVID-19). Copyright March 2020. https://s3.amazonaws.com/cdn.smfm.org/media/2263/COVID-19_Algorithm5.pdf .
Alfaraj SH, Al-Tawfiq JA, Memish ZA. (2019, Jun). Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection during pregnancy: Report of two cases & review of the literature. J Microbiol Immunol Infect. 52(3): 501-3. https://doi.org/10.1016/j.jmii.2018.04.005; PMid:29907538 PMCid:PMC7128238
Bachrach VR, Schwarz E, Bachrach LR. (2003). Breastfeeding and the risk of hospitalization for respiratory disease in infancy: a meta-analysis. Arch Pediatr Adolesc Med. 157: 237-243. https://doi.org/10.1001/archpedi.157.3.237; PMid:12622672
Bergman NJ, Linley LL, Fawcus SR. (2004). Randomized controlled trial of skin-to-skin contact from birth versus conventional incubator for physiological stabilization in 1200- to 2199-gram newborns. Acta Paediatr. 93: 779-785. https://doi.org/10.1111/j.1651-2227.2004.tb03018.x; PMid:15244227
Boelig R.C., Manuck T., Oliver E.A., Mascio Di D. et al. Labor and Delivery Guidance for COVID-19. The Jefferson University, Philadelphia, USA, University of North Carolina-Chapel Hill and UNC Health, Chapel Hill, NC, USA, Sapienza University of Rome, Italy School of Medicine, University of Naples Federico II, Naples, Italy. (in Press).
Bouthry E, Picone O, Hamdi G, Grangeot-Keros L, Ayoubi JM, Vauloup-Fellous C. (2014). Rubella and pregnancy: diagnosis, management and outcomes. Prenat Diagn. 34: 1246-53. https://doi.org/10.1002/pd.4467; PMid:25066688
Chen H GJ, Wang C, Luo F, Yu X, Zhang W et al. (2020). Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 395(10226): 809-15. https://doi.org/10.1016/S0140-6736(20)30360-3.
Cheung KS, Hung IF, Chan PP, Lung K et al. (2020). Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples from the Hong Kong Cohort and Systematic Review and Meta-analysis, Gastroenterology. https://doi.org/10.1053/j.gastro.2020.03.065; PMid:32251668 PMCid:PMC7194936.
Corman VM, Landt O, Kaiser M et al. (2020). Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 25: 2000045. https://doi.org/10.2807/1560-7917.ES.2020.25.3.2000045
CDС: Interim Infection Prevention and Control Recommendations for Healthcare Personnel During the Coronavirus Disease 2019 (COVID-19) Pandemic. Updated May 22, 2020. https://www.cdc.gov/coronavirus/2019-ncov/hcp/infection-control-recommendations.html.
CDС: If You Are Pregnant, Breastfeeding, or Caring for Young Children. Page last reviewed: June 25, 2020 Content source: National Center for Immunization and Respiratory Diseases (NCIRD), Division of Viral Diseases. https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/pregnancy-breastfeeding.html.
CDC's Guidance on Maintaining Childhood Immunizations During COVID-19 Pandemic is available on Resources for Clinics and Healthcare Facilities. Page last reviewed: June 9, 2020. Content source: National Center for Immunization and Respiratory Diseases. https://www.cdc.gov/vaccines/pandemic-guidance/index.html.
CDC: Coronavirus Disease 2019 (COVID-19) - cases in US. Page last reviewed: July 3, 2020 Content source: National Center for Immunization and Respiratory Diseases (NCIRD), Division of Viral Diseases. https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/cases-in-us.html.
CDC. How COVID-19 Spreads. 2020: https://www.cdc.gov/coronavirus/2019-ncov/about/transmission.html.
Di Mascio D, Khalil A, Saccone G et al. (2020). Outcome of Coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis. Am J Obstet Gynecol MFM In Press. https://doi.org/10.1016/j.ajogmf.2020.100107; PMid:32292902 PMCid:PMC7104131
Gottfredsson M. (2008). The Spanish flu in Iceland 1918. Lessons in medicine and history. Laeknabladid. 94: 737-45 (in Icelandic).
Halperin BA, Morris A, Mackinnon-Cameron D et al. (2011). Kinetics of the antibody response to tetanus-diphtheria acellular pertussis vaccine in women of childbearing age and postpartum women. Clin Infect Dis. 53: 885-892. https://doi.org/10.1093/cid/cir538; PMid:21946190
Huang C, Wang Y, Li X et al. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet; published online Jan24. https://doi.org/10.1016/S0140-6736(20)30183-5.
Immunization Schedules 2020: Page last reviewed: February 3, 2020. Content source: National Center for Immunization and Respiratory Diseases. https://www.cdc.gov/vaccines/schedules/hcp/imz/child-adolescent.html.
Jamieson DJ, Honein MA, Rasmussen SA, et al. (2009). H1N1 2009 influenza virus infection during pregnancy in the USA. Lancet. 374: 451-58. https://doi.org/10.1016/S0140-6736(09)61855-9
Lei D WC, Li C, Fang C, Yang W et al. (2020). Clinical characteristics of pregnancy with the 2019 novel coronavirus disease (COVID-19) infection. Chinese Journal Perinatal Medicine. 23(3).
Li Q, Guan X, Wu P et al. (2020, Jan 29). Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med. Published online. DOI 10.1056/NEJMoa2001316NEJMoa2001316.
Mojgan Karimi-Zarchi, Hossein Neamatzadeh, Seyed Alireza Dastgheib, Hajar Abbasi, Seyed Reza Mirjalili, Athena Behforouz, Farzad Ferdosian & Reza Bahrami. (2020). Vertical Transmission of Coronavirus Disease 19 (COVID-19) from Infected Pregnant Mothers to Neonates: A Review, Fetal and Pediatric Pathology. https://doi.org/10.1080/15513815.2020.1747120; PMid:32238084 PMCid:PMC7157948.
Moore ER, Bergman N, Anderson GC et al. (2016). Early skin-to-skin contact for mothers and their healthy newborn infants. Cochrane Data-base Syst Rev. 11: CD003519. https://doi.org/10.1002/14651858.CD003519.pub4; PMCid:PMC6464366
Morelius E, Theodorsson E, Nelson N. (2005). Salivary cortisol and mood and pain profiles during skin-to-skin care for an unselected group of mothers and infants in neonatal intensive care. Pediatrics. 116: 1105-1113. https://doi.org/10.1542/peds.2004-2440; PMid:16263996
Morgan BE, Horn AR, Bergman NJ. (2011). Should neonates sleep alone? Biol Psychiatry. 70: 817-825. https://doi.org/10.1016/j.biopsych.2011.06.018; PMid:21802659
National Health Commission of China. (2020, Jan 22). New coronavirus pneumonia prevention and control program. 4th edn. http://www.gov.cn/zhengce/zhengceku/2020-01/28/5472673/files/0f96c10cc09d4d36a6f9a9f0b42d972b.pdf (accessed Feb 4, 2020; in Chinese).
Niu Y, Yue H. (2020, Feb 5). Wuhan Tongji Hospital diagnoses first case of neonatal infection with new coronavirus. http://society. people.com.cn/n1/2020/0205/c1008-31572959.html (accessed Feb 7, 2020; in Chinese).
Puopolo KM, Hudak ML, Kimberlin DW, Cummings J. Initial recommendations: treatment of infants born to mothers with COVID-19. https://downloads.aap.org/AAP.
The State Council's Joint Prevention and Control Mechanism for Pneumonia Epidemic in Response to New Coronavirus Infection. Notice on prevention and control of pneumonia in children and pregnant women with new coronavirus infection. 2020, Feb 3. (accessed Feb 4, 2020; in Chinese). http://www.ljxw.gov.cn/news-93789.shtml.
Rasmussen SA, Smulian JC, Lednicky JA, Wen TS, Jamieson DJ. (2020, Feb 24). Coronavirus Disease 2019 (COVID-19) and Pregnancy: What obstetricians need to know. Am J Obstet Gyn. https://doi.org/10.1016/j.ajog.2020.02.017; PMid:32105680 PMCid:PMC7093856
Royal College of Midwives, Royal College of Obstetricians and Gynaecologists, Royal College of Paediatrics and Child Health, et al. Coronavirus (COVID-19) Infection in Pregnancy: Information for Health Care Professionals. Version 5. https://www.rcog.org.uk/globalassets/documents/guidelines/2020-03-28-covid19-pregnancy-guidance.pdf Accessed March 31, 2020.
Schoeman D, Fielding BC. (2019). Coronavirus envelope protein: current knowledge. Virol J; 16: 69. https://doi.org/10.1186/s12985-019-1182-0; PMid:31133031 PMCid:PMC6537279
Stuebe Alison. (2020). Should Infants Be Separated from Mothers with COVID-19? First, Do No Harm. Breastfeeding Medicine. 15; 5. Mary Ann Liebert, Inc. https://doi.org/10.1089/bfm.2020.29153.ams; PMid:32271625 PMCid:PMC7236243.
The Society for Maternal-Fetal Medicine (SMFM), Dotters-Latz S, Hughes B. Coronavirus (COVID-19) and Pregnancy: What Maternal-Fetal Medicine Subspecialists need to know. https://s3.amazonaws.com/cdn.smfm.org/media/2267/COVID19-updated_3-17-20_PDF.pdf (Accessed on March 23, 2020).
Shek CC, Ng PC, Fung GP, et al. (2003). Infants born to mothers with severe acute respiratory syndrome. Pediatrics. 112: e254. https://doi.org/10.1542/peds.112.4.e254; PMid:14523207
US Breastfeeding Committee: Infant and Young Child Feeding in Emergencies, including COVID-19. Page updated May 28, 2020. http://www.usbreastfeeding.org.
U.S. Department of Agriculture, Food and Nutrition Service: FNS Program Guidance on Human Pandemic Response. 03/13/2020. https://www.fns.usda.gov/disaster/pandemic.
Vaccines When Your Child Is Sick: Page last reviewed: May 14, 2019 https://www.cdc.gov/vaccines/parents/visit/sick-child.html.
Wong SF, Chow KM, Leung TN, Ng WF, Ng TK, Shek CC et al. (2004, Jul). Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. Am J Obstet Gynecol;191(1):292-7. https://doi.org/10.1016/j.ajog.2003.11.019; PMid:15295381 PMCid:PMC7137614
WHO. (2020, Jan 12). Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected. Interim guidance. https://www.who.int/docs/default-source/ coronaviruse/clinical-management-of-novel-cov.pdf (accessed Feb 4, 2020).
WHO. (2020, May 27) Clinical management of COVID-19: Overview: interim guidance. COVID-19: Clinical care: https://www.who.int/publications/i/item
WHO. (2020). Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases. Interim guidance.Jan17,2020.https://www.who.int/publications-detail/laboratory-testing-for-2019- novel-coronavirus-in-suspected-human-cases-20200117. Accessed Feb 4, 2020.
WHO. (2020). Home care for patients with COVID-19 presenting with mild symptoms and management of their contacts. Interim guidance 17 March 2020. COVID-19: Clinical care. https://www.who.int/publications/i/item/
WHO's. (2020). Guiding principles for immunization activities during the COVID-19 pandemic Interim guidance 26 March 2020. https://apps.who.int/iris/bitstream/handle
WHO. (2020). Coronavirus Disease (COVID-19) Dashboard: Data last updated: 2020/7/3, CES https://covid19.who.int
WHO: Coronavirus disease (COVID-2019) situation reports: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports/
De Wit E, van Doremalen N, Falzarano D, Munster VJ. (2016). SARS and MERS: recent insights into emerging coronaviruses. Nat Rev Microbiol. 14: 523–34. https://doi.org/10.1038/nrmicro.2016.81; PMid:27344959 PMCid:PMC7097822
Zeng L, Xia S, Yuan W et al. (2020, Mar 26). Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China. JAMA Pediatr. Epub ahead of print. https://doi.org/10.1001/jamapediatrics.2020.0878; PMid:32215598.
Zhang YZ. (2020). Novel 2019 coronavirus genome. Jan 21, 2020. http://virological.org/t/novel-2019-coronavirus-genome/319 (accessed Feb 4, 2020).
Zhang Z, Wang C, Gao CC. (2020, Feb 5). Neonatal coronavirus expert confirmed at 30 hours of birth: vertical transmission from mother to infant. http://www.cnr.cn/hubei/yuanchuang/20200205/t20200205_524961963. shtml (accessed Feb 10, 2020; in Chinese).
Zhou P, Yang XL, Wang XG et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020; published online Feb 3. https://doi.org/10.1038/s41586-020-2012-7; PMid:32015507 PMCid:PMC7095418.
Zhu N, Zhang D, Wang W et al. (2020). A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. Published online Jan 24. https://doi.org/10.1056/NEJMoa2001017; PMid:31978945 PMCid:PMC7092803.
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