Methodological approaches to the prevention of preeclampsia in high-risk pregnant women in perinatal practice

Authors

DOI:

https://doi.org/10.15574/PP.2026.1(105).119124

Keywords:

preeclampsia, pathophysiology, high-risk group, perinatal consequences, early diagnosis, prevention, methodological recommendations

Abstract

Preeclampsia is one of the most common and severe complications of pregnancy, which makes a significant contribution to the structure of maternal and perinatal morbidity and mortality. Despite the improvement of clinical protocols for pregnancy management, the frequency of severe forms of preeclampsia remains consistently high, especially among high-risk pregnant women.

Aim - to substantiate and systematize modern methodological approaches to the prevention of preeclampsia in high-risk pregnant women for their implementation in the practice of perinatal institutions.

This study was based on the analysis of international clinical recommendations (FIGO, ACOG, NICE), national pregnancy management protocols, as well as the results of randomized clinical trials and meta-analyses published in leading professional publications over the past 10 years. The methods of systematic analysis, generalization and expert assessment were applied.   Based on the analysis of international and national recommendations, a step-by-step algorithm of preventive measures is proposed, which is aimed at the early identification of risk groups, optimization of drug and non-drug prevention, as well as the reduction of adverse perinatal outcomes.

Conclusions. The proposed methodological approaches to the prevention of preeclampsia in high-risk pregnant women of high risk contribute to reducing the frequency of severe forms of the disease and improving perinatal outcomes. Early identification of risk factors and step-by-step prevention is an integral part of modern perinatal care.

The authors declare that there is no conflict of interest.

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Published

2026-03-28