The state of general immunity in women in labor with purulent wounds during hostilities
DOI:
https://doi.org/10.15574/PP.2024.98.55Keywords:
microbiological studies, purulent wound, obstetrics, purulent-septic complications, qualitative and quantitative composition of floraAbstract
Aim - to develop a more effective method of treating purulent wounds in obstetric practice based on the study of microbiological factors in the development of wound infection in women giving birth in wartime conditions.
Materials and methods. Studied the qualitative and quantitative composition of the wound microflora in 66 women in labor with purulent wounds of the anterior abdominal wall after caesarean section and perineum after episiotomy and perineotomy under martial law and compared it with the indicators of bacteriological studies in 76 women in labor with purulent wounds of the anterior abdominal wall after caesarean section and perineum after episio-, perineotomy in peacetime. Statistical data processing was carried out using the package of application programs "Microsoft Excel 5.0" and the standard version "Statistica 8.0". The difference in indicators was considered statistically significant at P<0.05.
Results and conclusions. Based on the analysis of microbiological studies, it was determined that the causative agent of purulent wounds in obstetric practice during the war against the background of stress and greater suppression of both general and local immunity is opportunistically pathogenic flora, among which both gram-positive and gram-negative flora dominate, and in peacetime At that time, the most frequent causative agent of purulent wounds in women in labor was gram-positive flora, which was isolated both in monoculture and in association with gram-negative and anaerobic microorganisms.
The first place among gram-positive flora is occupied by St. Epidermidis and gram-negative - Acinetobacter. In 37.9%, inflammatory processes in the tissues of postoperative wounds arise under the influence of the symbiotic relationship of aerobic-anaerobic microorganisms, and in 57.6% - the association of aerobic microorganisms.
The research was carried out in accordance with the principles of the Declaration of Helsinki. The research protocol was approved by the Local Ethics Committee of the institution mentioned in the work. Informed consent of the parents was obtained from the mothers in labor for the research.
The authors declare no conflict of interest.
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