An analysis of perinatal outcomes in pregnant women with arterial hypertension in Poland and Ukraine during times of conflict
DOI:
https://doi.org/10.15574/PP.2023.94.70Keywords:
hypertension, chronic hypertension, blood pressure, hypertensive disorders, preeclampsia, gestational hypertension, depression, perinatal outcomesAbstract
Hypertensive problems are present in 10% of all pregnancies. Hypertensive disorders in pregnancy constitute one of the reasonsfor maternal death and perinatal too in the world.Women with hypertension are always at higher risk for preterm birth than women without disorder. The article is dedicated to analyzing pregnancy and its consequences, including perinatal outcomes, in women with arterial hypertension. The analysis was conducted at two powerful medical centers - the Princess Anna maternity hospital in city Warsaw, Poland, and the KNP KMPB No. 5 in city Kyiv, Ukraine. The prolonged war in Ukraine has complicated the timely diagnosis and proper treatment of pathological conditions. To assess this problem, two groups were created: control and experimental, and a total of 366 pregnant patients were studied. In Warsaw, 206 patients were analyzed, while in the Kyiv maternity hospital, 160 patients were analyzed. During the analysis, one of the conclusions drawn was that chronic hypertension during pregnancy is strongly associated with pregnancy complications and negatively affected by other complicating factors such as maternal age, previous pregnancy complications, and obesity.
Separate groups were identified and calculated for complications in each center separately. The degree of depression among pregnant women undergoing examination was also taken into account, and those who needed help from specialists were referred to psychologists.
The authors declare no conflicts of interest.
References
World Health Organization. (2019). Hypertensive disorders of pregnancy. URL: https://www.who.int/news-room/q-a-detail/hypertensive-disorders-of-pregnancy.
Ghulmiyyah L, Sibai B. (2012). Maternal mortality from preeclampsia/eclampsia. Seminars in perinatology. 36(1): 56-59. https://doi.org/10.1053/j.semperi.2011.09.011; PMid:22280867
Bdzan A. (2015). Hypertension in pregnancy - causes and risk factors. Journal of Pre-Clinical and Clinical Research. 9(1): 30-33.
American College of Obstetricians and Gynecologists. (2019). Hypertension in pregnancy. ACOG Practice Bulletin. 202: 1-17. https://doi.org/10.1097/AOG.0000000000003292.
https://doi.org/10.1097/AOG.0000000000003292
Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. (2000). American Journal of Obstetrics and Gynecology. 183(1): S1-S22. https://doi.org/10.1067/mob.2000.103327.
Przybylowska K, Dudziak M, Bojarska-Junak A. (2019). Influence of hypertension on pregnancy complications and perinatal outcomes. Journal of Perinatal Medicine. 47(4): 391-398. https://doi.org/10.1515/jpm-2018-0253.
Muczyń Ł, Zajkowska A. (2016). Hypertension in pregnancy - Risk factors and outcomes. Ginekologia Polska. 87(12): 828-831. https://doi.org/10.5603/GP.a2016.0141.
Schneider S, Hoeft B, Freerksen N, Fischer B, Roehrig S, Yamamoto S, Maul H. (2010). Neonatal complications and risk factors among women with gestational diabetes mellitus - wiley online library. (n.d.). Retrieved November 13, 2022, from https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/j.1600-0412.2010.01040.x. https://doi.org/10.1111/j.1600-0412.2010.01040.x; PMid:21306307
Moodley J, Soma-Pillay P, Buchmann E, Pattinson RC. (2019, Sep 13). Hypertensive disorders in pregnancy: 2019 National guideline. S Afr Med J. 109(9): 12723. PMID: 31635598.
Seely EW, Ecker J. (2014, Mar 18). Chronic hypertension in pregnancy. Circulation. 129(11): 1254-1261. https://doi.org/10.1161/CIRCULATIONAHA.113.003904; PMid:24637432
Bramham K, Parnell B, Nelson-Piercy C, Seed PT, Poston L, Chappell LC. (2014, Apr 15). Chronic hypertension and pregnancy outcomes: systematic review and meta-analysis. BMJ. 348: g2301. https://doi.org/10.1136/bmj.g2301; PMid:24735917 PMCid:PMC3988319
Alsnes IV, Vatten LJ, Fraser A, Bjørngaard JH, Rich-Edwards J, Romundstad PR, Åsvold BO. (2017, Apr). Hypertension in Pregnancy and Offspring Cardiovascular Risk in Young Adulthood: Prospective and Sibling Studies in the HUNT Study (Nord-Trøndelag Health Study) in Norway. Hypertension. 69(4): 591-598. Epub 2017 Feb 21. https://doi.org/10.1161/HYPERTENSIONAHA.116.08414; PMid:28223467
Seely EW, Ecker J. (2014, Mar 18). Chronic hypertension in pregnancy. Circulation. 129(11): 1254-1261. https://doi.org/10.1161/CIRCULATIONAHA.113.003904; PMid:24637432
Bateman BT, Huybrechts KF, Fischer MA, Seely EW, Ecker JL, Oberg AS et al. (2015, Mar). Chronic hypertension in pregnancy and the risk of congenital malformations: A cohort study. American journal of obstetrics and gynecology. 212(3): 337.e1-14. Epub 2014 Sep 28. https://doi.org/10.1016/j.ajog.2014.09.031; PMid:25265405 PMCid:PMC4346443
Peahl AF, Smith RD, Moniz MH. (2020, September). Prenatal care redesign: Creating Flexible Maternity Care models through virtual care. American journal of obstetrics and gynecology. 223(3):389.e1-389.e10. Epub 2020 May 17. https://doi.org/10.1016/j.ajog.2020.05.029; PMid:32425200 PMCid:PMC7231494
ACOG. (2020, Jun). Gestational hypertension and preeclampsia. Practice Bulletin. 222. URL: https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2020/06/gestational-hypertension-and-preeclampsia.
ACOG. (2001). Chronic hypertension in pregnancy. ACOG Committee on Practice Bulletins. Obstetrics and gynecology. 98(1); suppl: 177-185. https://doi.org/10.1097/00006250-200107000-00032
Anderson GD, Carr DB. (2009). Effect of pregnancy on the pharmacokinetics of antihypertensive drugs. Clinical pharmacokinetics. 48(3): 159-168. https://doi.org/10.2165/00003088-200948030-00002; PMid:19385709
Cockburn J, Moar VA, Ounsted M, Redman CW. (1982). Final report of study on hypertension during pregnancy: the effects of specific treatment on the growth and development of the children. Lancet. 1(8273): 647-649. https://doi.org/10.1016/S0140-6736(82)92202-4; PMid:6121965
Magee LA. (2001). Drugs in pregnancy. Antihypertensives. Best practice & research Clinical obstetrics & gynaecology. 15(6): 827-845. https://doi.org/10.1053/beog.2001.0232; PMid:11800527
Bramham K, Parnell B, Nelson-Piercy C, Seed PT, Poston L, Chappell LC. (2014, Apr 15). Chronic hypertension and pregnancy outcomes: systematic review and meta-analysis. BMJ. 348: g2301. https://doi.org/10.1136/bmj.g2301; PMid:24735917 PMCid:PMC3988319
MOZ (no date). URL: https://moz.gov.ua/ (Accessed: March 28, 2023).
Zdorove rebenka. (2012). 5(40). [Здоровье ребенка. (2012). 5(40)]. URL: http://www.mif-ua.com/archive/article/32962.
Aktualne Wydanie (no date) Psychiatria. Available at: https://journals.viamedica.pl/psychiatria (Accessed: March 28, 2023).
Archives of Psychiatry and psychotherapy (no date) Archives of Psychiatry and Psychotherapy. Available at: https://www.archivespp.pl/ (Accessed: March 28, 2023).
World Health Organization. (2018). WHO recommendations on antenatal care for a positive pregnancy experience. https://www.who.int/reproductivehealth/publications/maternal_perinatal_health/anc-positive-pregnancy-experience/en/.
National Institute for Health and Care Excellence. (2019). Hypertension in pregnancy: Diagnosis and management. https://www.nice.org.uk/guidance/ng133/chapter/Recommendations#management-of-hypertension-in-pregnancy.
Gavin NI, Gaynes BN, Lohr KN, Meltzer-Brody S, Gartlehner G, Swinson T. (2005). Perinatal depression: a systematic review of prevalence and incidence. Obstetrics and gynecology. 106(5): 1071-1083. https://doi.org/10.1097/01.AOG.0000183597.31630.db; PMid:16260528
Labetalol oral: Uses, side effects, interactions, pictures, warnings & dosing. (no date). WebMD. WebMD. URL: https://www.webmd.com/drugs/2/drug-7212/labetalol-oral/details.
Labetalol use during pregnancy. (no date). Drugs.com. URL: https://www.drugs.com/pregnancy/labetalol.html.
ACOG. (no date). Hypertension bundle labetalol algorithm. URL: https://www.acog.org/-/media/project/acog/acogorg/files/forms/districts/smi-hypertension-bundle-labetalol-algorithm.pdf.
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